The biological role of casomorphins

The literature review is devoted to biologically active metabolites of casein — the results its hydrolysis oligopeptides casomorphins. These peptides with a chain length 4 11 amino acids are derived from milk β-casein and released during digestion, both in vivo vitro. Caseomorphins exhibit opioid pharmacological activity due binding μ-receptors located central nervous system, gastrointestinal tract some immune cells. Understanding biological role caseomorphins mammals, including humans, their effect on organs systems, will bring specialists closer deciphering etiology whole group diseases.